	公開日期	標題	作者	來源出版物	scopus	WOS
1	2024	Doxazosin inhibits vasculogenic mimicry in human non‑small cell lung cancer through inhibition of the VEGF‑A/VE‑cadherin/mTOR/MMP pathway	Hsu, Jui-Ling; Leu, Wohn-Jenn; LIH-CHING HSU ; Hsieh, Chia-Hsun; JIH-HWA GUH	Oncology letters
2	2024	Cardenolide glycosides sensitize gefitinib-induced apoptosis in non-small cell lung cancer: inhibition of Na+/K+-ATPase serving as a switch-on mechanism	Du, Chi-Min; Leu, Wohn-Jenn; Jiang, Yi-Huei; Chan, She-Hung; Chen, Ih-Sheng; Chang, Hsun-Shuo; LIH-CHING HSU ; Hsu, Jui-Ling; JIH-HWA GUH	Naunyn-Schmiedeberg's archives of pharmacology
3	2024	A novel HDAC6 inhibitor interferes microtubule dynamics and spindle assembly checkpoint and sensitizes cisplatin-induced apoptosis in castration-resistant prostate cancer	Ye, Pei-Chen; Leu, Wohn-Jenn; Yeh, Tsung-Yu; Hsu, Yu-Tung; Lin, Yi-Chin; Wei, Zi-Yuan; Chen, Yi-Chin; Chiang, Yi-Chang; Hsu, Jui-Ling; Chan, She-Hung; LIH-CHING HSU ; JI-WANG CHERN ; CHAO-WU YU ; JIH-HWA GUH	The Prostate
4	2024	Structure-based design, synthesis and biological evaluation of N-substituted 6H-thiochromeno[2,3–c]quinolin-12(12H)-one as potential breast cancer drugs	Sumitra, Maryam Rachmawati; Chen, Lung Ching; Tsai, Wei Chen; Ansar, Muhamad; Lawal, Bashir; Mokgautsi, Ntlotlang; JIH-HWA GUH ; Wu, Alexander T.H.; Huang, Hsu Shan	Arabian Journal of Chemistry
5	2023	Mechanistic study of dual-function inhibitors targeting topoisomerase II and Rad51-mediated DNA repair pathway against castration-resistant prostate cancer	Chiang, Yi-Chang; Leu, Wohn-Jenn; Chen, Yi-Chin; Ye, Pei-Chen; Hsu, Yu-Tung; Hsiao, Yu-Chi; Hsu, Jui-Ling; Chan, She-Hung; LIH-CHING HSU ; Huang, Hsu-Shan; JIH-HWA GUH	The Prostate
6	2023	Anticancer Activity and Molecular Mechanisms of an Ursodeoxycholic Acid Methyl Ester-Dihydroartemisinin Hybrid via a Triazole Linkage in Hepatocellular Carcinoma Cells	Hsu, Ya-Fen; FAN-LU KUNG ; Huang, Tzu-En; Deng, Yi-Ning; JIH-HWA GUH ; Marchetti, Paolo; Marchesi, Elena; Perrone, Daniela; Navacchia, Maria Luisa; LIH-CHING HSU	Molecules (Basel, Switzerland)	3	3
7	2022	Discovery of New Glucose Uptake Inhibitors as Potential Anticancer Agents by Non-Radioactive Cell-Based Assays	Hung, Hsueh-Chih; Li, Li-Cheng; JIH-HWA GUH ; FAN-LU KUNG ; LIH-CHING HSU	Molecules (Basel, Switzerland)	3	1
8	2022	The Combination of a Novel GLUT1 Inhibitor and Cisplatin Synergistically Inhibits Breast Cancer Cell Growth By Enhancing the DNA Damaging Effect and Modulating the Akt/mTOR and MAPK Signaling Pathways	Weng, Hao-Cheng; Sung, Chieh-Ju; Hsu, Jui-Ling; Leu, Wohn-Jenn; JIH-HWA GUH ; FAN-LU KUNG ; LIH-CHING HSU	Frontiers in pharmacology	9	6
9	2021	Antileukemic Natural Product Induced Both Apoptotic and Pyroptotic Programmed Cell Death and Differentiation Effect	Leu, Wohn-Jenn; Chang, Hsun-Shuo; Chen, Ih-Sheng; JIH-HWA GUH ; Chan, She-Hung	International journal of molecular sciences	5	5
10	2021	Autophagic Activation and Decrease of Plasma Membrane Cholesterol Contribute to Anticancer Activities in Non-Small Cell Lung Cancer	Hsu, Jui-Ling; Leu, Wohn-Jenn; Zhong, Nan-Shan; JIH-HWA GUH	Molecules (Basel, Switzerland)	5	3
11	2021	Characterization of a fluorescent glucose derivative 1-NBDG and its application in the identification of natural SGLT1/2 inhibitors	Kao, Ting-Yu; Wu, Hwa-Wei; SHOEI-SHENG LEE ; PI-HUI LIANG ; JIH-HWA GUH ; LIH-CHING HSU	Journal of food and drug analysis	3	2
12	2020	Chalcones Display Anti-NLRP3 Inflammasome Activity in Macrophages through Inhibition of Both Priming and Activation Steps-Structure-Activity-Relationship and Mechanism Studies	Leu W.-J.; Chu J.-C.; Hsu J.-L.; Du C.-M.; Jiang Y.-H.; LIH-CHING HSU ; Huang W.-J.; JIH-HWA GUH	Molecules (Basel, Switzerland)	8	8
13	2020	Synthesis, distribution analysis and mechanism studies of N-acyl glucosamine-bearing oleanolic saponins	Juang Y.-P.; Lin Y.-Y.; Chan S.-H.; Chang C.-K.; Shie J.-J.; Hsieh Y.S.Y.; JIH-HWA GUH ; PI-HUI LIANG	Bioorganic Chemistry	9	8
14	2020	Evaluation of the Anticancer Activity of a Bile Acid-Dihydroartemisinin Hybrid Ursodeoxycholic-Dihydroartemisinin in Hepatocellular Carcinoma Cells	Huang T.-E.; Deng Y.-N.; Hsu J.-L.; Leu W.-J.; Marchesi E.; Capobianco M.L.; Marchetti P.; Navacchia M.L.; JIH-HWA GUH ; Perrone D.; LIH-CHING HSU	Frontiers in Pharmacology	19	18
15	2020	Phosphodiesterase Type 5 Inhibitors Synergize Vincristine in Killing Castration-Resistant Prostate Cancer Through Amplifying Mitotic Arrest Signaling	Hsu J.-L.; Leu W.-J.; LIH-CHING HSU ; Ho C.-H.; SHIH-PING LIU ; JIH-HWA GUH	Frontiers in Oncology	11	9
16	2020	Ascleposide, a natural cardenolide, induces anticancer signaling in human castration-resistant prostatic cancer through Na+/K+-ATPase internalization and tubulin acetylation	Leu W.-J.; Wang C.-T.; Hsu J.-L.; Chen I.-S.; Chang H.-S.; JIH-HWA GUH	Prostate	9	8
17	2020	The (+)-brevipolide H displays anticancer activity against human castration-resistant prostate cancer: The role of oxidative stress and Akt/mTOR/p70S6K dependent pathways in G1 checkpoint arrest and apoptosis	Sheng Y.-H.; Leu W.-J.; Chen C.-N.; Hsu J.-L.; Liu Y.-T.; LIH-CHING HSU ; Hou D.-R.; JIH-HWA GUH	Molecules	4	4
18	2020	Mechanistic study of triazole based aminodiol derivatives in leukemic cells—crosstalk between mitochondrial stress-involved apoptosis and autophagy	Chan S.-H.; Leu W.-J.; Swain S.P.; Hsu J.-L.; Hou D.-R.; JIH-HWA GUH	International Journal of Molecular Sciences	1	2
19	2020	Pharmacological Targeting of Vacuolar H+-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer	Wang Y.; Zhang L.; Wei Y.; Huang W.; Li L.; Wu A.-A.; Dastur A.; Greninger P.; Bray W.M.; Zhang C.-S.; Li M.; Lian W.; Hu Z.; Wang X.; Liu G.; Yao L.; JIH-HWA GUH ; Chen L.; Wang H.-R.; Zhou D.; Lin S.-C.; Xu Q.; Shen Y.; Zhang J.; Jurica M.S.; Benes C.H.; Deng X.	Cell Chemical Biology	16	13
20	2020	Discovery of novel agents on spindle assembly checkpoint to sensitize vinorelbine-induced mitotic cell death against human non-small cell lung cancers	Chang Y.-C.; Tseng Y.-L.; Leu W.-J.; Du C.-M.; Jiang Y.-H.; LIH-CHING HSU ; Hsu J.-L.; Hou D.-R.; JIH-HWA GUH	International Journal of Molecular Sciences	2	1
21	2019	Phosphodiesterase type 5 (PDE5) inhibitors sensitize topoisomerase II inhibitors in killing prostate cancer through PDE5-independent impairment of HR and NHEJ DNA repair systems	Chang J.-F.; Hsu J.-L.; Sheng Y.-H.; Leu W.-J.; Yu C.-C.; Chan S.-H.; Chan M.-L.; LIH-CHING HSU ; SHIH-PING LIU ; JIH-HWA GUH	Frontiers in Oncology	11	13
22	2019	Extract from plectranthus amboinicus inhibit maturation and release of interleukin 1β through inhibition of NF-κB nuclear translocation and NLRP3 inflammasome activation	Leu W.-J.; Chen J.-C.; JIH-HWA GUH	Frontiers in Pharmacology	28	29
23	2019	Synthesis and biological evaluation of anthra[1,9-cd]pyrazol-6(2H)-one scaffold derivatives as potential anticancer agents	Chen T.-C.; JIH-HWA GUH ; Hsu H.-W.; Chen C.-L.; Lee C.-C.; Wu C.-L.; Lee Y.-R.; JING-JER LIN ; Yu D.-S.; Huang H.-S.	Arabian Journal of Chemistry	8	7
24	2019	Design, synthesis and biological evaluation of tetracyclic azafluorenone derivatives with topoisomerase I inhibitory properties as potential anticancer agents	Chen T.-C.; Yu D.-S.; Chen S.-J.; Chen C.-L.; Lee C.-C.; Hsieh Y.-Y.; Chang L.-C.; JIH-HWA GUH ; JING-JER LIN ; Huang H.-S.	Arabian Journal of Chemistry	11	11
25	2019	The combination of MK-2206 and WZB117 exerts a synergistic cytotoxic effect against breast cancer cells	Li Y.-L.; Weng H.-C.; Hsu J.-L.; SHU-WHA LIN ; JIH-HWA GUH ; LIH-CHING HSU	Frontiers in Pharmacology	24	22
26	2019	Dihydroartemisinin–Bile Acid Hybridization as an Effective Approach to Enhance Dihydroartemisinin Anticancer Activity	Marchesi E.; Chinaglia N.; Capobianco M.L.; Marchetti P.; Huang T.-E.; Weng H.-C.; JIH-HWA GUH ; LIH-CHING HSU ; Perrone D.; Navacchia M.L.	ChemMedChem	17	17
27	2018	Retraction of "Development of Novel Adenosine Monophosphate-Activated Protein Kinase Activators"	JIH-HWA GUH ; Chang, Wei-Ling; Yang, Jian; Lee, Su-Lin; Wei, Shuo; Wang, Dasheng; Kulp, Samuel K; Chen, Ching-Shih	Journal of medicinal chemistry
28	2018	An integrated approach to elucidate signaling pathways of dioscin-induced apoptosis, energy metabolism and differentiation in acute myeloid leukemia	Chan S.-H.; PI-HUI LIANG ; JIH-HWA GUH	Naunyn-Schmiedeberg's Archives of Pharmacology	11	11
29	2018	Design, synthesis and cytotoxic activity of N-Modified oleanolic saponins bearing A glucosamine	Lin, You-Yu; Chan, She-Hung; Juang, Yu-Pu; Hsiao, Hsin-Min; JIH-HWA GUH ; PI-HUI LIANG	European Journal of Medicinal Chemistry	17	16
30	2018	Synthesis, characterization and cancer cell growth inhibition activity of ruthenium(II) complexes bearing bidentate pyrrole-imine ligands	Chen G.-H.; Leu W.-J.; JIH-HWA GUH ; Lin C.-H.; Huang J.-H.	Journal of Organometallic Chemistry	7	5
31	2018	Ruthenium (II) complexes containing dehydroacetic acid and its imine derivative ligands. Synthesis, characterization and cancer cell growth anti-proliferation activity (GI50) study	Chen K.-H.; Lin T.-H.; Hsu T.-E.; Li Y.-J.; Chen G.-H.; Leu W.-J.; JIH-HWA GUH ; Lin C.-H.; Huang J.-H.	Journal of Organometallic Chemistry	8	6
32	2018	Para-toluenesulfonamide induces anti-tumor activity through Akt-dependent and -independent mTOR/p70S6K pathway: Roles of lipid raft and cholesterol contents	Hsu J.-L.; Leu W.-J.; LIH-CHING HSU ; SHIH-PING LIU ; Zhong N.-S.; JIH-HWA GUH	Frontiers in Pharmacology	10	19
33	2018	Discovery of aliphatic-chain hydroxamates containing indole derivatives with potent class I histone deacetylase inhibitory activities	Chao S.-W.; Chen L.-C.; Yu C.-C.; Liu C.-Y.; Lin T.E.; JIH-HWA GUH ; Wang C.-Y.; Chen C.-Y.; Hsu K.-C.; Huang W.-J.	European Journal of Medicinal Chemistry	20	17
34	2017	Enantiomerically pure β-dipeptide derivative induces anticancer activity against human hormone-refractory prostate cancer through both PI3K/Akt-dependent and -independent pathways	Chan M.-L.; Yu C.-C.; Hsu J.-L.; Leu W.-J.; Chan S.-H.; LIH-CHING HSU ; SHIH-PING LIU ; Ivantcova P.M.; Dogan ?.; Br?se S.; Kudryavtsev K.V.; JIH-HWA GUH	Oncotarget	8	8
35	2016	Synthesis and characterization of ruthenium compounds incorporating keto-amine ligands. The applications of catalytic transfer hydrogenation and cancer cell inhibition	Lin T.-H.; Das K.; Datta A.; Leu W.-J.; Hsiao H.-C.; Lin C.-H.; JIH-HWA GUH ; Huang J.-H.	Journal of Organometallic Chemistry	8	8
36	2016	Non-immunosuppressive triazole-based small molecule induces anticancer activity against human hormone-refractory prostate cancers: The role in inhibition of PI3K/AKT/mTOR and c-Myc signaling pathways	Leu W.-J.; Swain S.P.; Chan S.-H.; Hsu J.-L.; SHIH-PING LIU ; Chan M.-L.; Yu C.-C.; LIH-CHING HSU ; Chou Y.-L.; Chang W.-L.; Hou D.-R.; JIH-HWA GUH	Oncotarget	14	14
37	2016	ERK Activation Globally Downregulates miRNAs through Phosphorylating Exportin-5	Sun H.-L.; Cui R.; Zhou J.; Teng K.-Y.; Hsiao Y.-H.; Nakanishi K.; Fassan M.; Luo Z.; Shi G.; Tili E.; Kutay H.; Lovat F.; Vicentini C.; Huang H.-L.; Wang S.-W.; Kim T.; Zanesi N.; Jeon Y.-J.; Lee T.J.; JIH-HWA GUH ; Hung M.-C.; Ghoshal K.; Teng C.-M.; Peng Y.; Croce C.M.	Cancer Cell	114	102
38	2016	Hemiasterlin derivative (R)(S)(S)-BF65 and Akt inhibitor MK-2206 synergistically inhibit SKOV3 ovarian cancer cell growth	Lai W.-T.; Cheng K.-L.; Baruchello R.; Rondanin R.; Marchetti P.; Simoni D.; Lee R.M.; JIH-HWA GUH ; LIH-CHING HSU	Biochemical Pharmacology	7	7
39	2015	Ring fusion strategy for synthesis and lead optimization of sulfur-substituted anthra[1,2-c[[1,2,5]thiadiazole-6,11-dione derivatives as promising scaffold of antitumor agents	Lee Y.-R.; Chen T.-C.; Lee C.-C.; Chen C.-L.; Ahmed Ali A.A.; Tikhomirov A.; JIH-HWA GUH ; Yu D.-S.; Huang H.-S.	European Journal of Medicinal Chemistry	25	23
40	2015	Catalytic transfer hydrogenation and anticancer activity of arene-ruthenium compounds incorporating bi-dentate precursors	Chang Y.-H.; Leu W.-J.; Datta A.; Hsiao H.-C.; Lin C.-H.; JIH-HWA GUH ; Huang J.-H.	Dalton Transactions	17	16
41	2015	Tubulin-binding agents down-regulate matrix metalloproteinase-2 and -9 in human hormone-refractory prostate cancer cells - A critical role of Cdk1 in mitotic entry	Chang W.-L.; Yu C.-C.; Chen C.-S.; JIH-HWA GUH	Biochemical Pharmacology	19	19
42	2015	Menthols as Chiral Auxiliaries for Asymmetric Cycloadditive Oligomerization: Syntheses and Studies of β-Proline Hexamers	Kudryavtsev K.V.; Ivantcova P.M.; Muhle-Goll C.; Churakov A.V.; Sokolov M.N.; Dyuba A.V.; Arutyunyan A.M.; Howard J.A.K.; Yu C.-C.; JIH-HWA GUH ; Zefirov N.S.; Br?se S.	Organic Letters	14	15
43	2015	Epi-reevesioside F inhibits Na+/K+-ATPase, causing cytosolic acidification, Bak activation and apoptosis in glioblastoma	Hsu J.-L.; Liu F.-L.; LIH-CHING HSU ; Chang H.-S.; Leu W.-J.; Yu C.-C.; Chang W.-L.; Chen I.-S.; FAN-LU KUNG ; JIH-HWA GUH	Oncotarget	6	5
44	2015	Structural studies and anticancer activity of a novel class of β-peptides	Kudryavtsev K.V.; Yu C.-C.; Ivantcova P.M.; Polshakov V.I.; Churakov A.V.; Br?se S.; Zefirov N.S.; JIH-HWA GUH	Chemistry - An Asian Journal	15	14
45	2015	Cytotoxic protobassic acid glycosides from Planchonella obovata leaf	Chen H.-Y.; JIH-HWA GUH ; Chan S.-H.; SHOEI-SHENG LEE	Phytochemistry Letters	7	7
46	2015	Repurposing of phentolamine as a potential anticancer agent against human castration-resistant prostate cancer: A central role on microtubule stabilization and mitochondrial apoptosis pathway	Ho C.-H.; Hsu J.-L.; SHIH-PING LIU ; LIH-CHING HSU ; Chang W.-L.; Chao C.C.-K.; JIH-HWA GUH	Prostate	14	14
47	2015	KUD773, a phenylthiazole derivative, displays anticancer activity in human hormone-refractory prostate cancers through inhibition of tubulin polymerization and anti-Aurora a activity	Yu C.-C.; SHIH-PING LIU ; Hsu J.-L.; Hsu J.T.A.; Kudryavtsev K.; JIH-HWA GUH	Journal of Biomedical Science	1	1
48	2015	Repurposing of nitroxoline as a potential anticancer agent against human prostate cancer - A crucial role on AMPK/mTOR signaling pathway and the interplay with Chk2 activation	Chang W.-L.; LIH-CHING HSU ; Leu W.-J.; Chen C.-S.; JIH-HWA GUH	Oncotarget	39	35
49	2015	Zerumbone, a ginger sesquiterpene, induces apoptosis and autophagy in human hormone-refractory prostate cancers through tubulin binding and crosstalk between endoplasmic reticulum stress and mitochondrial insult	Chan M.-L.; Liang J.-W.; LIH-CHING HSU ; Chang W.-L.; SHOEI-SHENG LEE ; JIH-HWA GUH	Naunyn-Schmiedeberg's Archives of Pharmacology	39	33
50	2014	Synthesis and anti-cancer activity of a glycosyl library of \varvec{N} N -acetylglucosamine-bearing oleanolic acid	Zeng, Yi-Bing; Hsiao, Hsin-Min; Chan, She-Hung; Wang, Ying-Hsin; Lin, You-Yu; Kuo, Yu-Hsuan; JIH-HWA GUH ; PI-HUI LIANG	Molecular Diversity	14
51	2014	A general synthetic strategy and the anti-proliferation properties on prostate cancer cell lines for natural phenylethanoid glycosides	Mulani S.K.; JIH-HWA GUH ; Mong K.-K.T.	Organic and Biomolecular Chemistry	36	34
52	2014	The Akt inhibitor MK-2206 enhances the cytotoxicity of paclitaxel (Taxol) and cisplatin in ovarian cancer cells	Lin Y.-H.; Chen B.Y.-H.; Lai W.-T.; Wu S.-F.; JIH-HWA GUH ; ANN-LII CHENG ; LIH-CHING HSU	Naunyn-Schmiedeberg's Archives of Pharmacology	34	32
53	2014	Ring fusion strategy for the synthesis of anthra[2,3-d ]oxazole-2-thione-5,10-dione homologues as DNA topoisomerase inhibitors and as antitumor agents	Chen C.-L.; Liu F.-L.; Lee C.-C.; Chen T.-C.; Chang W.-W.; JIH-HWA GUH ; Ahmed Ali A.A.; Chang D.-M.; Huang H.-S.	European Journal of Medicinal Chemistry	20	17
54	2014	Reevesioside A, a cardenolide glycoside, induces anticancer activity against human hormone-refractory prostate cancers through suppression of c-myc expression and induction of G1 arrest of the cell cycle	Leu W.-J.; Chang H.-S.; Chan S.-H.; Hsu J.-L.; Yu C.-C.; LIH-CHING HSU ; Chen I.-S.; JIH-HWA GUH	PLoS ONE	26	24
55	2014	A novel small molecule hybrid of vorinostat and DACA displays anticancer activity against human hormone-refractory metastatic prostate cancer through dual inhibition of histone deacetylase and topoisomerase i	Yu C.-C.; Pan S.-L.; Chao S.-W.; SHIH-PING LIU ; Hsu J.-L.; Yang Y.-C.; TSAI-KUN LI ; Huang W.-J.; JIH-HWA GUH	Biochemical Pharmacology	29	28
56	2014	Calanquinone A induces anti-glioblastoma activity through glutathione-involved DNA damage and AMPK activation	Liu F.-L.; Hsu J.-L.; Lee Y.-J.; Dong Y.-S.; FAN-LU KUNG ; Chen C.-S.; JIH-HWA GUH	European Journal of Pharmacology	4	3
57	2014	Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption	Che-Jen Hsiao; George Hsiao; Wei-Lin Chen; Shih-Wei Wang; Chun-Ping Chiang; Liu L.-Y.; JIH-HWA GUH ; Tzong-Huei Lee ; Chi-Li Chung	Journal of Natural Products	46	43
58	2014	A unique amidoanthraquinone derivative displays antiproliferative activity against human hormone-refractory metastatic prostate cancers through activation of LKB1-AMPK-mTOR signaling pathway	Hsu J.-L.; SHIH-PING LIU ; Lee C.-C.; LIH-CHING HSU ; Ho Y.-F.; Huang H.-S.; JIH-HWA GUH	Naunyn-Schmiedeberg's Archives of Pharmacology	13	12
59	2014	Terfenadine induces anti-proliferative and apoptotic activities in human hormone-refractory prostate cancer through histamine receptor-independent Mcl-1 cleavage and Bak up-regulation	Wang W.-T.; Chen Y.-H.; Hsu J.-L.; Leu W.-J.; Yu C.-C.; Chan S.-H.; Ho Y.-F.; LIH-CHING HSU ; JIH-HWA GUH	Naunyn-Schmiedeberg's Archives of Pharmacology	27	25
60	2014	Moniliformediquinone induces in vitro and in vivo antitumor activity through glutathione involved DNA damage response and mitochondrial stress in human hormone refractory prostate cancer	Hsu J.-L.; Lee Y.-J.; Leu W.-J.; Dong Y.-S.; Pan S.-L.; Uang B.-J.; JIH-HWA GUH	Journal of Urology	12	11
61	2013	Total synthesis of 14,21-diepi-squamocin-K	Liu C.-W.; Yeh T.-C.; Chen C.-H.; Yu C.-C.; Chen C.-S.; Hou D.-R.; JIH-HWA GUH	Tetrahedron	6	5
62	2013	Synthesis of a chlorogenin glycoside library using an orthogonal protecting group strategy	Wang Y.-H.; Yeh H.-W.; Wang H.-W.; Yu C.-C.; JIH-HWA GUH ; Liu D.-Z.; PI-HUI LIANG	Carbohydrate Research	13	13
63	2013	Reevesioside F induces potent and efficient anti-proliferative and apoptotic activities through Na+/K+-ATPase α3 subunit-involved mitochondrial stress and amplification of caspase cascades	Chan S.-H.; Leu W.-J.; LIH-CHING HSU ; Chang H.-S.; Hwang T.-L.; Chen I.-S.; Chen C.-S.; JIH-HWA GUH	Biochemical Pharmacology	17	15
64	2013	Erratum: Anti-angiogenic effects and mechanism of prazosin (The Prostate (2011) 71 (976-984))	Liao C.-H.; JIH-HWA GUH ; SHIH-CHIEH CHUEH ; HONG-JENG YU	Prostate	0	0
65	2013	2-(1H-Imidazol-1-yl)-4-[3-(trifluoromethyl)phenyl]-1,3-thiazole	Kudryavtsev K.V.; Churakov A.V.; JIH-HWA GUH	Acta Crystallographica Section E: Structure Reports Online	1	0
66	2013	A novel hydroxysuberamide derivative potentiates MG132-mediated anticancer activity against human hormone refractory prostate cancers - The role of histone deacetylase and endoplasmic reticulum stress	Chen Y.-C.; Huang W.-J.; Hsu J.-L.; Yu C.-C.; Wang W.-T.; JIH-HWA GUH	Prostate	6	6
67	2013	Ardisianone, a natural benzoquinone, efficiently induces apoptosis in human hormone-refractory prostate cancers through mitochondrial damage stress and survivin downregulation	Yu C.-C.; Wu P.-J.; Hsu J.-L.; Ho Y.-F.; LIH-CHING HSU ; Chang Y.-J.; Chang H.-S.; Chen I.-S.; JIH-HWA GUH	Prostate	25	22
68	2013	Structure-based design, synthesis and evaluation of novel anthra[1,2-d]imidazole-6,11-dione derivatives as telomerase inhibitors and potential for cancer polypharmacology	Chen C.-L.; Chang D.-M.; Chen T.-C.; Lee C.-C.; Hsieh H.-H.; Huang F.-C.; Huang K.-F.; JIH-HWA GUH ; JING-JER LIN ; Huang H.-S.	European Journal of Medicinal Chemistry	35	34
69	2013	Design, synthesis and antiproliferative evaluation of fluorenone analogs with DNA topoisomerase i inhibitory properties	Lee C.-C.; Chang D.-M.; Huang K.-F.; Chen C.-L.; Chen T.-C.; Lo Y.; JIH-HWA GUH ; Huang H.-S.	Bioorganic and Medicinal Chemistry	20	18
70	2012	Pim-1 knockdown potentiates paclitaxel-induced apoptosis in human hormone-refractory prostate cancers through inhibition of NHEJ DNA repair	Hsu J.-L.; Leong P.-K.; Ho Y.-F.; LIH-CHING HSU ; Lu P.-H.; Chen C.-S.; JIH-HWA GUH	Cancer Letters	23	17
71	2012	Pycnidione, a fungus-derived agent, induces cell cycle arrest and apoptosis in A549 human lung cancer cells	Che-Jen Hsiao; Shih-Hsin Hsiao; Wei-Lin Chen; JIH-HWA GUH ; George Hsiao; Yen-Ju Chan; Tzong-Huei Lee ; Chi-Li Chung	Chemico-Biological Interactions	35	27
72	2012	Synthesis, antiproliferative activities and telomerase inhibition evaluation of novel asymmetrical 1,2-disubstituted amidoanthraquinone derivatives	Lee C.-C.; Huang K.-F.; Lin P.-Y.; Huang F.-C.; Chen C.-L.; Chen T.-C.; JIH-HWA GUH ; JING-JER LIN ; Huang H.-S.	European Journal of Medicinal Chemistry	27	23
73	2012	Protopine, a novel microtubule-stabilizing agent, causes mitotic arrest and apoptotic cell death in human hormone-refractory prostate cancer cell lines	Chen C.-H.; Liao C.-H.; Chang Y.-L.; JIH-HWA GUH ; Pan S.-L.; Teng C.-M.	Cancer Letters	54	49
74	2012	Chemical modification and anticancer effect of prenylated flavanones from Taiwanese propolis	Chen C.-N.; Hsiao C.-J.; SHOEI-SHENG LEE ; JIH-HWA GUH ; Chiang P.-C.; Huang C.-C.; Huang W.-J.	Natural Product Research	26	22
75	2012	Antroquinonol, a natural ubiquinone derivative, induces a cross talk between apoptosis, autophagy and senescence in human pancreatic carcinoma cells	Yu C.-C.; Chiang P.-C.; Lu P.-H.; Kuo M.-T.; Wen W.-C.; Chen P.; JIH-HWA GUH	Journal of Nutritional Biochemistry	67	61
76	2012	Rottlerin potentiates camptothecin-induced cytotoxicity in human hormone refractory prostate cancers through increased formation and stabilization of topoisomerase I-DNA cleavage complexes in a PKCδ-independent pathway	Hsu J.-L.; Ho Y.-F.; TSAI-KUN LI ; Chen C.-S.; LIH-CHING HSU ; JIH-HWA GUH	Biochemical Pharmacology	18	16
77	2012	Bioactive diterpenes from Callicarpa longissima	Liu Y.-W.; Cheng Y.-B.; Liaw C.-C.; Chen C.-H.; JIH-HWA GUH ; Hwang T.-L.; Tsai J.-S.; WON-BO WANG ; Shen Y.-C.	Journal of Natural Products	34	31
78	2011	Total synthesis of moniliformediquinone and calanquinone A as potent inhibitors for breast cancer	Thangaraj S.; Tsao W.-S.; Luo Y.-W.; Lee Y.-J.; Chang C.-F.; Lin C.-C.; Uang B.-J.; Yu C.-C.; JIH-HWA GUH ; Teng C.-M.	Tetrahedron	19	17
79	2011	Synthesis and evaluation of aliphatic-chain hydroxamates capped with osthole derivatives as histone deacetylase inhibitors	Huang W.-J.; CHING-CHOW CHEN ; Chao S.-W.; Yu C.-C.; Yang C.-Y.; JIH-HWA GUH ; Lin Y.-C.; Kuo C.-I.; Yang P.; Chang C.-I.	European Journal of Medicinal Chemistry	37	35
80	2011	ICAM-1 and AMPK regulate cell detachment and apoptosis by N-methyl-N'-nitro-N-nitrosoguanidine, a widely spread environmental chemical, in human hormone-refractory prostate cancers	Chen Y.-C.; Lu P.-H.; Hsu J.-L.; Yu C.-C.; JIH-HWA GUH	Toxicology and Applied Pharmacology	8	8
81	2011	Targeting energy metabolic and oncogenic signaling pathways in triple-negative breast cancer by a novel adenosine monophosphate-activated protein kinase (AMPK) activator	Lee K.-H.; Hsu E.-C.; JIH-HWA GUH ; Yang H.-C.; Wang D.; Kulp S.K.; Shapiro C.L.; Chen C.-S.	Journal of Biological Chemistry	89	90
82	2011	WJ9708012 exerts anticancer activity through PKC-α related crosstalk of mitochondrial and endoplasmic reticulum stresses in human hormone-refractory prostate cancer cells	Kuo T.-C.; Huang W.-J.; JIH-HWA GUH	Acta Pharmacologica Sinica	8	7
83	2011	Anti-angiogenic effects and mechanism of prazosin	Liao C.-H.; JIH-HWA GUH ; SHIH-CHIEH CHUEH ; HONG-JENG YU	Prostate	25	27
84	2011	Paclitaxel induces apoptosis through activation of nuclear protein kinase C-δ and subsequent activation of Golgi associated Cdk1 in human hormone refractory prostate cancer	Lu P.-H.; Yu C.-C.; Chiang P.-C.; Chen Y.-C.; Ho Y.-F.; FAN-LU KUNG ; JIH-HWA GUH	Journal of Urology	16	14
85	2011	Costunolide induces apoptosis through nuclear calcium2+ overload and DNA damage response in human prostate cancer	Hsu J.-L.; Pan S.-L.; Ho Y.-F.; Hwang T.-L.; FAN-LU KUNG ; JIH-HWA GUH	Journal of Urology	49	46
86	2011	A unique P-glycoprotein interacting agent displays anticancer activity against hepatocellular carcinoma through inhibition of GRP78 and mTOR pathways	Kuo T.-C.; Chiang P.-C.; Yu C.-C.; Nakagawa-Goto K.; Bastow K.F.; Lee K.-H.; JIH-HWA GUH	Biochemical Pharmacology	18	15
87	2010	Moscatilin repressed lipopolysaccharide-induced hif-1α accumulation and NF-κB activation in murine raw264.7 cells	Liu Y.-N.; Pan S.-L.; Peng C.-Y.; Huang D.-Y.; JIH-HWA GUH ; Chen C.-C.; Shen C.-C.; Teng C.-M.	Shock	28	26
88	2010	Methoxychalcone induces cell-cycle arrest and apoptosis in human hormone-resistant prostate cancer cells through PI 3-kinase-independent inhibition of mTOR pathways	Sun Y.-W.; Huang W.-J.; Hsiao C.-J.; Chen Y.-C.; Lu P.-H.; JIH-HWA GUH	Prostate	14	12
89	2010	Cryptocaryone, a Natural Dihydrochalcone, Induces Apoptosis in Human Androgen Independent Prostate Cancer Cells by Death Receptor Clustering in Lipid Raft and Nonraft Compartments	Chen Y.-C.; FAN-LU KUNG ; Tsai I.-L.; Chou T.-H.; Chen I.-S.; JIH-HWA GUH	Journal of Urology	29	31
90	2010	Moscatilin, a bibenzyl derivative from the India orchid Dendrobrium loddigesii, suppresses tumor angiogenesis and growth in vitro and in vivo	Tsai A.-C.; Pan S.-L.; Liao C.-H.; JIH-HWA GUH ; Wang S.-W.; Sun H.-L.; Liu Y.-N.; Chen C.-C.; Shen C.-C.; Chang Y.-L.; Teng C.-M.	Cancer Letters	59	48
91	2010	Antroquinonol displays anticancer potential against human hepatocellular carcinoma cells: A crucial role of AMPK and mTOR pathways	Chiang P.-C.; Lin S.-C.; Pan S.-L.; CHING-HUA KUO ; Tsai I.-L.; Kuo M.-T.; Wen W.-C.; Chen P.; JIH-HWA GUH	Biochemical Pharmacology	114	106
92	2010	The indazole derivative YD-3 specifically inhibits thrombin-induced angiogenesis in vitro and in vivo	Peng C.-Y.; Pan S.-L.; Pai H.-C.; Tsai A.-C.; JIH-HWA GUH ; Chang Y.-L.; Kuo S.-C.; Lee F.-Y.; Teng C.-M.	Shock	5	5
93	2010	2-Phenyl-5-(pyrrolidin-1-yl)-1-(3,4,5-trimethoxybenzyl)-1H-benzimidazole, a benzimidazole derivative, inhibits growth of human prostate cancer cells by affecting tubulin and c-Jun N-terminal kinase	Chang W.-L.; Chang C.-S.; Chiang P.-C.; Ho Y.-F.; Liu J.-F.; Chang K.-W.; JIH-HWA GUH	British Journal of Pharmacology	30	25
94	2010	Anticancer activity of a cyclooxygenase inhibitor, CX9051, in human prostate cancer cells: The roles of NF-κB and crosstalk between the extrinsic and intrinsic apoptotic pathways	Huang C.-H.; JIH-HWA GUH ; Chen G.S.; Lu P.-H.; Chern J.-W.	Naunyn-Schmiedeberg's Archives of Pharmacology	7	7
95	2009	Combined treatment with denbinobin and fas ligand has a synergistic cytotoxic effect in human pancreatic adenocarcinoma Bxpc-3 Cells	CHIA-RON YANG ; JIH-HWA GUH ; Teng C.M.; Chen C.C.; Chen P.H.	British Journal of Pharmacology	16	14
96	2009	Tunicamycin induces resistance to camptothecin and etoposide in human hepatocellular carcinoma cells: Role of cell-cycle arrest and GRP78	Hsu J.-L.; Chiang P.-C.; JIH-HWA GUH	Naunyn-Schmiedeberg's Archives of Pharmacology	34	30
97	2009	Evodiamine represses hypoxia-induced inflammatory proteins expression and hypoxia-inducible factor 1α accumulation in RAW264.7	Liu Y.-N.; Pan S.-L.; Liao C.-H.; Huang D.-Y.; JIH-HWA GUH ; Peng C.-Y.; Chang Y.-L.; Teng C.-M.	Shock	67	58
98	2009	abeo-taxane diterpenoids from the Taiwanese yew Taxus sumatrana	Wang S.-S.; Abd El-Razek M.H.; Chen Y.-G.; Chien C.-T.; JIH-HWA GUH ; Kuo Y.-H.; Shen Y.-C.	Chemistry and Biodiversity	2	1
99	2008	Synthesis, DNA binding, and cytotoxicity of 1,4-bis(2-amino-ethylamino)anthraquinone-amino acid conjugates	LING-WEI HSIN ; Wang H.-P.; Kao P.-H.; Lee O.; Chen W.-R.; Chen H.-W.; JIH-HWA GUH ; Chan Y.-L.; His C.-P.; Yang M.-S.; TSAI-KUN LI ; Lee C.-H.	Bioorganic and Medicinal Chemistry	45	41
100	2008	Elucidation of susceptible factors to endoplasmic reticulum stress-mediated anticancer activity in human hepatocellular carcinoma	Chiang P.-C.; Hsu J.-L.; Yeh T.-C.; Pan S.-L.; JIH-HWA GUH	Naunyn-Schmiedeberg's Archives of Pharmacology	8	6
101	2008	WRC-213, an l-methionine-conjugated mitoxantrone derivative, displays anticancer activity with reduced cardiotoxicity and drug resistance: Identification of topoisomerase II inhibition and apoptotic machinery in prostate cancers	Hsiao C.-J.; TSAI-KUN LI ; Chan Y.-L.; LING-WEI HSIN ; Liao C.-H.; Lee C.-H.; Lyu P.-C.; JIH-HWA GUH	Biochemical Pharmacology	35	32
102	2008	Denbinobin induces apoptosis by apoptosis-inducing factor releasing and DNA damage in human colorectal cancer HCT-116 cells	Chen T.-H.; Pan S.-L.; JIH-HWA GUH ; Chen C.-C.; Huang Y.-T.; Pai H.-C.; Teng C.-M.	Naunyn-Schmiedeberg's Archives of Pharmacology	21	16
103	2008	New bioactive clerodane diterpenoids from the roots of Casearia membranacea	Chen C.-Y.; Cheng Y.-B.; Chen S.-Y.; Chien C.-T.; Kuo Y.-H.; JIH-HWA GUH ; Khalil A.T.; Shen Y.-C.	Chemistry and Biodiversity	26	27
104	2008	Baicalein attenuates intimal hyperplasia after rat carotid balloon injury through arresting cell-cycle progression and inhibiting ERK, Akt, and NF-κB activity in vascular smooth-muscle cells	Peng C.-Y.; Pan S.-L.; Huang Y.-W.; JIH-HWA GUH ; Chang Y.-L.; Teng C.-M.	Naunyn-Schmiedeberg's Archives of Pharmacology	42	39
105	2008	The p38 mitogen-activated protein kinase pathway plays a critical role in PAR2-induced endothelial IL-8 production and leukocyte adhesion	Pan S.L.; Tao K.Y.; JIH-HWA GUH ; Sun H.L.; Huang D.Y.; Chang Y.L.; Teng C.M.	Shock	18	16
106	2008	Mana-Hox displays anticancer activity against prostate cancer cells through tubulin depolymerization and DNA damage stress	Hsiao C.-J.; Ho Y.-F.; Hsu J.T.-A.; Chang W.-L.; Chen Y.-C.; Shen Y.-C.; Lyu P.-C.; JIH-HWA GUH	Naunyn-Schmiedeberg's Archives of Pharmacology	9	9
107	2008	Moscatilin induces apoptosis in human colorectal cancer cells: A crucial role of c-Jun NH2-terminal protein kinase activation caused by tubulin depolymerization and DNA damage	Chen T.-H.; Pan S.-L.; JIH-HWA GUH ; Liao C.-H.; Huang D.-Y.; Chen C.-C.; Teng C.-M.	Clinical Cancer Research	51	41
108	2008	YC-1 induces heat shock protein 70 expression and prevents oxidized LDL-mediated apoptosis in vascular smooth muscle cells	Liu Y.-N.; Pan S.-L.; Peng C.-Y.; Huang D.-Y.; JIH-HWA GUH ; Kuo S.-C.; Lee F.-Y.; Teng C.-M.	Shock	12	10
109	2008	CHM-1, a novel synthetic quinolone with potent and selective antimitotic antitumor activity against human hepatocellular carcinoma in vitro and in vivo	Wang S.-W.; Pan S.-L.; Huang Y.-C.; JIH-HWA GUH ; Chiang P.-C.; Huang D.-Y.; Kuo S.-C.; Lee K.-H.; Teng C.-M.	Molecular Cancer Therapeutics	65	59
110	2008	YC-1 induces apoptosis of human renal carcinoma A498 cells in vitro and in vivo through activation of the JNK pathway	Wu S.Y.; Pan S.L.; Chen T.H.; Liao C.H.; Huang D.Y.; JIH-HWA GUH ; Chang Y.L.; Kuo S.C.; Lee F.Y.; Teng C.M.	British Journal of Pharmacology	25	25
111	2007	Four new briarane diterpenoids from the gorgonian coral Junceella fragilis	Shen Y.-C.; Chen Y.-H.; Hwang T.-L.; JIH-HWA GUH ; Khalil A.T.	Helvetica Chimica Acta	39	33
112	2007	CHM-1 inhibits hepatocyte growth factor-induced invasion of SK-Hep-1 human hepatocellular carcinoma cells by suppressing matrix metalloproteinase-9 expression	Wang S.-W.; Pan S.-L.; Peng C.-Y.; Huang D.-Y.; Tsai A.-C.; Chang Y.-L.; JIH-HWA GUH ; Kuo S.-C.; Lee K.-H.; Teng C.-M.	Cancer Letters	24	22
113	2007	Quinolone analogue inhibits tubulin polymerization and induces apoptosis via Cdk1-involved signaling pathways	Chen Y.-C.; Lu P.-H.; Pan S.-L.; Teng C.-M.; Kuo S.-C.; Lin T.-P.; Ho Y.-F.; Huang Y.-C.; JIH-HWA GUH	Biochemical Pharmacology	58	59
114	2007	Ilimaquinone, a marine sponge metabolite, displays anticancer activity via GADD153-mediated pathway	Lu P.-H.; SHIH-CHIEH CHUEH ; FAN-LU KUNG ; Pan S.-L.; Shen Y.-C.; JIH-HWA GUH	European Journal of Pharmacology	52	47
115	2007	Prazosin displays anticancer activity against human prostate cancers: Targeting DNA and cell cycle	Lin S.-C.; SHIH-CHIEH CHUEH ; Hsiao C.-J.; TSAI-KUN LI ; Chen T.-H.; Liao C.-H.; Lyu P.-C.; JIH-HWA GUH	Neoplasia	61	58
116	2007	YC-1 inhibits HIF-1 expression in prostate cancer cells: Contribution of Akt/NF-κB signaling to HIF-1α accumulation during hypoxia	Sun H.-L.; Liu Y.-N.; Huang Y.-T.; Pan S.-L.; Huang D.-Y.; JIH-HWA GUH ; Lee F.-Y.; Kuo S.-C.; Teng C.-M.	Oncogene	162	158
117	2007	Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult	Yeh T.-C.; Chiang P.-C.; TSAI-KUN LI ; Hsu J.-L.; CHUN-JUNG LIN ; Wang S.-W.; Peng C.-Y.; JIH-HWA GUH	Biochemical Pharmacology	123	110
118	2006	Investigation of anti-tumor mechanisms of K2154: Characterization of tubulin isotypes, mitotic arrest and apoptotic machinery	Lu P.-H.; FAN-LU KUNG ; Kuo S.-C.; SHIH-CHIEH CHUEH ; JIH-HWA GUH	Naunyn-Schmiedeberg's Archives of Pharmacology	8	8
119	2006	YC-1 [3-(5′-hydroxymethyl-2′-furyl)-1-benzyl indazole] inhibits neointima formation in balloon-injured rat carotid through suppression of expressions and activities of matrix metalloproteinases 2 and 9	Liu Y.-N.; Pan S.-L.; Peng C.-Y.; JIH-HWA GUH ; Huang D.-M.; Chang Y.-L.; Lin C.-H.; Pai H.-C.; Kuo S.-C.; Lee F.-Y.; Teng C.-M.	Journal of Pharmacology and Experimental Therapeutics	39	33
120	2006	Alisol B acetate, a triterpene from Alismatis rhizoma, induces Bax nuclear translocation and apoptosis in human hormone-resistant prostate cancer PC-3 cells	Huang Y.-T.; Huang D.-M.; SHIH-CHIEH CHUEH ; Teng C.-M.; JIH-HWA GUH	Cancer Letters	87	79
121	2006	Induction of Fas clustering and apoptosis by coral prostanoid in human hormone-resistant prostate cancer cells	Chiang P.-C.; FAN-LU KUNG ; Huang D.-M.; TSAI-KUN LI ; Fan J.-R.; Pan S.-L.; Shen Y.-C.; JIH-HWA GUH	European Journal of Pharmacology	23	24
122	2005	Three new taxane diterpenoids from Taxus sumatrana	Shen Y.-C.; Cheng K.-C.; Lin Y.-C.; Cheng Y.-B.; Khalil A.T.; JIH-HWA GUH ; Chien C.-T.; Teng C.-M.; Chang Y.-T.	Journal of Natural Products	19	15
123	2005	Induction of endoplasmic reticulum stress and apoptosis by a marine prostanoid in human hepatocellular carcinoma	Chiang P.-C.; CHUNG-LIANG CHIEN ; Pan S.-L.; WEN-PIN CHEN ; Teng C.-M.; Shen Y.-C.; JIH-HWA GUH	Journal of Hepatology	44	38
124	2005	A potential role of YC-I on the inhibition of cytokine release in peripheral blood mononuclear leukocytes and endotoxemic mouse models	Pan S.-L.; JIH-HWA GUH ; Peng C.-Y.; Chang Y.-L.; Cheng F.-C.; Chang J.-H.; Kuo S.-C.; Lee F.-Y.; Teng C.-H.	Thrombosis and Haemostasis	32	31
125	2005	CIL-102 interacts with microtubule polymerization and causes mitotic arrest following apoptosis in the human prostate cancer PC-3 cell line	Huang Y.-T.; Huang D.-M.; JIH-HWA GUH ; Chen I.-L.; Tzeng C.-C.; Teng C.-M.	Journal of Biological Chemistry	43	44
126	2005	Denbinobin-mediated anticancer effect in human K562 leukemia cells: Role in tubulin polymerization and Bcr-Abl activity	Huang Y.-C.; JIH-HWA GUH ; Teng C.-M.	Journal of Biomedical Science	32	27
127	2005	YC-1 suppresses constitutive nuclear factor-κB activation and induces apoptosis in human prostate cancer cells	Huang Y.-T.; Pan S.-L.; JIH-HWA GUH ; Chang Y.-L.; Lee F.-Y.; Kuo S.-C.; Teng C.-M.	Molecular Cancer Therapeutics	45	43
128	2005	Induction of mitotic arrest and apoptosis in human prostate cancer PC-3 cells by evodiamine	Huang D.-M.; JIH-HWA GUH ; Huang Y.-T.; SHIH-CHIEH CHUEH ; Chiang P.-C.; Teng C.-M.	Journal of Urology	49	44
129	2005	Antitumor mechanism of evodiamine, a constituent from Chinese herb Evodiae fructus, in human multiple-drug resistant breast cancer NCI/ADR-RES cells in vitro and in vivo	Liao C.-H.; Pan S.-L.; JIH-HWA GUH ; Chang Y.-L.; Pai H.-C.; Lin C.-H.; Teng C.-M.	Carcinogenesis	122	117
130	2005	Two new sesquiterpene lactones from Ixeris chinensis	Khalil A.T.; Shen Y.-C.; JIH-HWA GUH ; Cheng S.-Y.	Chemical and Pharmaceutical Bulletin	16	14
131	2005	YC-1 [3-(5′-hydroxymethyl-2′-furyl)-1-benzyl indazole] inhibits endothelial cell functions induced by angiogenic factors in vitro and angiogenesis in vivo models	Pan S.-L.; JIH-HWA GUH ; Peng C.-Y.; Wang S.-W.; Chang Y.-L.; Cheng F.-C.; Chang J.-H.; Kuo S.-C.; Lee F.-Y.; Teng C.-M.	Journal of Pharmacology and Experimental Therapeutics	55	53
132	2005	Investigation of anticancer mechanism of clavulone II, a coral cyclopentenone prostaglandin analog, in human acute promyelocytic leukemia	Huang Y.-C.; JIH-HWA GUH ; Shen Y.-C.; Teng C.-M.	Journal of Biomedical Science	11	10
133	2005	YC-1 [3-(5′-hydroxymethyl-2′-furyl)-1-benzyl indazole] exhibits a novel antiproliferative effect and arrests the cell cycle in G 0-G1 in human hepatocellular carcinoma cells	Wang S.-W.; Pan S.-L.; JIH-HWA GUH ; Chen H.-L.; Huang D.-M.; Chang Y.-L.; Kuo S.-C.; Lee F.-Y.; Teng C.-M.	Journal of Pharmacology and Experimental Therapeutics	47	47
134	2004	New pentacyclic polyketide dimeric peroxides from a Taiwanese marine sponge Petrosia elastica	Shen Y.C.; Prakash C.V.S.; JIH-HWA GUH	Tetrahedron Letters	14	12
135	2004	Modulation of Anti-Adhesion Molecule MUC-1 Is Associated with Arctiin-Induced Growth Inhibition in PC-3 Cells	Huang D.-M.; JIH-HWA GUH ; SHIH-CHIEH CHUEH ; Teng C.-M.	Prostate	25	22
136	2004	Investigation of ouabain-induced anticancer effect in human androgen-independent prostate cancer PC-3 cells	Huang Y.-T.; SHIH-CHIEH CHUEH ; Teng C.-M.; JIH-HWA GUH	Biochemical Pharmacology	101	93
137	2004	Induction of mitotic arrest and apoptosis by evodiamine in human leukemic T-lymphocytes	Huang Y.-C.; JIH-HWA GUH ; Teng C.-M.	Life Sciences	64	59
138	2004	Genistein inversely affects tubulin-binding agent-induced apoptosis in human breast cancer cells	Liao C.-H.; Pan S.-L.; JIH-HWA GUH ; Teng C.-M.	Biochemical Pharmacology	31	27
139	2004	Flavonol glycosides and cytotoxic triterpenoids from Alphitonia philippinensis	Jou S.-J.; Chen C.-H.; JIH-HWA GUH ; Lee C.-N.; SHOEI-SHENG LEE	Journal of the Chinese Chemical Society	34	32
140	2004	Two new cytotoxic clerodane diterpenoids from Casearia membranacea	Shen Y.-C.; Wang L.-T.; Wang C.-H.; Khalil A.T.; JIH-HWA GUH	Chemical and Pharmaceutical Bulletin	35	35
141	2004	Investigation of extrinsic and intrinsic apoptosis pathways of new clerodane diterpenoids in human prostate cancer PC-3 cells	Huang D.-M.; Shen Y.-C.; Wu C.; Huang Y.-T.; FAN-LU KUNG ; Teng C.-M.; JIH-HWA GUH	European Journal of Pharmacology	48	45
142	2004	The indazole derivative YD-3 inhibits thrombin-induced vascular smooth muscle cell proliferation and attenuates intimal thickening after balloon injury	Peng C.-Y.; Pan S.-L.; JIH-HWA GUH ; Liu Y.-N.; Chang Y.-L.; Kuo S.-C.; Lee F.-Y.; Teng C.-M.	Thrombosis and Haemostasis	21	21
143	2004	New Prostanoids with Cytotoxic Activity from Taiwanese Octocoral Clavularia viridis	Shen Y.-C.; Cheng Y.-B.; Lin Y.-C.; JIH-HWA GUH ; Teng C.-M.; Ko C.-L.	Journal of Natural Products	46	42
144	2004	YC-1 prevents sodium nitroprusside-mediated apoptosis in vascular smooth muscle cells	Pan S.L.; JIH-HWA GUH ; Chang Y.L.; Kuo S.C.; Lee F.Y.; Teng C.M.	Cardiovascular Research	36	32
145	2004	New Cytotoxic Clerodane Diterpenoids from the Leaves and Twigs of Casearia membranacea	Shen Y.-C.; Wang C.-H.; Cheng Y.-B.; Wang L.-T.; JIH-HWA GUH ; Chien C.-T.; Khalil A.T.	Journal of Natural Products	49	47
146	2004	Armepavine oxalate induces cell death on CCRF-CEM leukemia cell line through an apoptotic pathway	Jow G.-M.; Wu Y.-C.; JIH-HWA GUH ; Teng C.-M.	Life Sciences	13	12
147	2003	Potentiation of tumor necrosis factor-α expression by YC-1 in alveolar macrophages through a cyclic GMP-independent pathway	Hwang T.-L.; Wu C.-C.; JIH-HWA GUH ; Teng C.-M.	Biochemical Pharmacology	21	17
148	2003	Pharmacological evaluation of several major ingredients of Chinese herbal medicines in human hepatoma Hep3B cells	Chou C.C.; Pan S.L.; Teng C.M.; JIH-HWA GUH	European Journal of Pharmaceutical Sciences	85	76
149	2003	A novel secobetulinic acid 3,4-lactone from Viburnum aboricolum	Ku Y.-L.; Rao G.V.; Chen C.-H.; Wu C.; JIH-HWA GUH ; SHOEI-SHENG LEE	Helvetica Chimica Acta	15	12
150	2003	Identification of apoptotic and antiangiogenic activities of terazosin in human prostate cancer and endothelial cells	Pan S.-L.; JIH-HWA GUH ; Huang Y.-W.; Chern J.-W.; Chou J.-Y.; Teng C.-M.	Journal of Urology	27	25
151	2003	Investigation of anticancer mechanism of thiadiazole-based compound in human non-small cell lung cancer A549 cells	Chou J.-Y.; Lai S.-Y.; Pan S.-L.; Jow G.-M.; Chern J.-W.; JIH-HWA GUH	Biochemical Pharmacology	147	123
152	2003	Esculetin inhibits Ras-mediated cell proliferation and attenuates vascular restenosis following angioplasty in rats	Pan S.-L.; Huang Y.-W.; JIH-HWA GUH ; Chang Y.-L.; Peng C.-Y.; Teng C.-M.	Biochemical Pharmacology	67	62
153	2002	Characterization of some novel α1-adrenoceptor antagonists in human hyperplastic prostate	SHIH-CHIEH CHUEH ; Chern J.-W.; Choong C.-M.; JIH-HWA GUH ; Teng C.-M.	European Journal of Pharmacology	6	6
154	2002	1-Benzyl-3-(5′-hydroxymethyl-2′-furyl)-indazole (YC-1) derivatives as novel inhibitors against sodium nitroprusside-induced apoptosis	Lien J.-C.; Lee F.-Y.; Huang L.-J.; Pan S.-L.; JIH-HWA GUH ; Teng C.-M.; Kuo S.-C.	Journal of Medicinal Chemistry	27	23
155	2002	Inhibition of Ras-mediated cell proliferation by benzyloxybenzaldehyde	Pan S.-L.; JIH-HWA GUH ; Huang Y.-W.; Chang Y.-L.; Chang C.-Y.; Huang L.-J.; Kuo S.-C.; Teng C.-M.	Journal of biomedical science	11	9
156	2002	Effect of a potent cyclooxygenase inhibitor, 5-ethyl-4-methoxy-2-phenylquinoline (KTC-5), on human platelets	Liao C.-H.; Chang Y.-L.; JIH-HWA GUH ; Kuo S.-C.; Huang L.-J.; Teng C.-M.	Journal of Pharmacy and Pharmacology	3	3
157	2002	Cardiac glycosides induce resistance to tubulin-dependent anticancer drugs in androgen-independent human prostate cancer	Huang D.-M.; JIH-HWA GUH ; Huang Y.-T.; SHIH-CHIEH CHUEH ; Wang H.-P.; Teng C.-M.	Journal of biomedical science	12	12
158	2001	Inhibition of the expression of inducible nitric oxide synthase and cyclooxygenase-2 in macrophages by 7HQ derivatives: Involvement of IκB-α stabilization	Huang Y.C.; JIH-HWA GUH ; Cheng Z.J.; Chang Y.L.; Hwang T.L.; Liao C.H.; Tzeng C.C.; Teng C.M.	European Journal of Pharmacology	10	8
159	2001	Dual effects of ouabain on the regulation of proliferation and apoptosis in human prostatic smooth muscle cells	SHIH-CHIEH CHUEH ; JIH-HWA GUH ; Chen J.; Lai M.-K.; Teng C.-M.	Journal of Urology	80	78
160	2001	Inhibitory effect of DCDC on lipopolysaccharide-induced nitric oxide synthesis in RAW 264.7 cells	Huang Y.-C.; JIH-HWA GUH ; Cheng Z.-J.; Chang Y.-L.; Hwang T.-L.; Lin C.-N.; Teng C.-M.	Life Sciences	39	36
161	2000	Effects of ouabain on tension response and [3H]noradrenaline release in human prostate	JIH-HWA GUH ; SHIH-CHIEH CHUEH ; Teng C.-M.	Journal of Urology	5	5
162	1999	Investigation of the effects of some alkaloidal α1-adrenoceptor antagonists on human hyperplastic prostate	JIH-HWA GUH ; Hsieh C.-H.; Teng C.-M.	European Journal of Pharmacology	14	11
163	1998	Retraction: Mechanism of anti-proliferation caused by YC-1, an indazole derivative, in cultured rat A10 vascular smooth-muscle cells (Biochemical Journal (1995) 306 (787-792))	Cheng, Zhijiao; JIH-HWA GUH ; Lee, Fangyu; Kuo, Shengchen	Biochemical Journal
164	1998	Erratum: Mechanism of catecholamine-induced proliferation of vascular smooth muscle cells (Circulation (1996) 94 (547-554))	Yu S.-M.; Tsai S.-Y.; JIH-HWA GUH ; Ko F.-N.; Teng C.-M.; Ou J.T.	Circulation	0	0
165	1998	Mechanism of anti-proliferation caused by YC-1, an indazole derivative, in cultured rat A10 vascular smooth-muscle cells.	Cheng Z.J.; JIH-HWA GUH ; Lee F.Y.; Kuo S.C.	The Biochemical journal	1	0
166	1998	Cell proliferation in human prostatic smooth muscle cells involves the modulation of protein kinase C isozymes	JIH-HWA GUH ; SHIH-CHIEH CHUEH ; Hwang T.L.; Chen J.; Teng C.M.	European Journal of Pharmacology	16	16
167	1998	Antiproliferative effect in human prostatic smooth muscle cells by nitric oxide donor	JIH-HWA GUH ; Hwang T.-L.; Ko F.-N.; SHIH-CHIEH CHUEH ; Lai M.-K.; Teng C.-M.	Molecular Pharmacology	75	68
168	1997	Correction: Mechanism of anti-proliferation caused by YC-1, an indazole derivative, in cultured rat A10 vascular smooth-muscle cells (Biochemical Journal (1995) 306 (787-792))	Yu S.M.; Cheng Z.J.; JIH-HWA GUH ; Lee F.Y.; Kuo S.C.	Biochemical Journal	1	0
169	1996	Ouabain-induced increases in resting tone of human hyperplastic prostate following repeated noradrenaline and electrical field stimulation	JIH-HWA GUH ; Ko F.-N.; SHIH-CHIEH CHUEH ; Lai M.-K.; Teng C.-M.	British Journal of Pharmacology	8	8
170	1996	Antiproliferative effect in rat vascular smooth muscle cells by osthole, isolated from Angelica pubescens	JIH-HWA GUH ; Yu S.-M.; Ko F.-N.; Wu T.S.; Teng C.-M.	European Journal of Pharmacology	61	56
171	1996	Inhibition by tamsulosin of tension responses of human hyperplastic prostate to electrical field stimulation	SHIH-CHIEH CHUEH ; JIH-HWA GUH ; Chen J.; Lai M.-K.; Ko F.-N.; Teng C.-M.	European Journal of Pharmacology	26	24
172	1996	Mechanism of catecholamine-induced proliferation of vascular smooth muscle cells	Yu S.-M.; Tsai S.-Y.; JIH-HWA GUH ; Ko F.-N.; Teng C.-M.; Ou J.T.	Circulation	87	82
173	1995	CSH72—A Specific Antagonist of Platelet?activating Factor in Rabbit Platelets	JIH-HWA GUH ; KO F.?N.; LEE C.?S.; TENG C.?M.	Pharmacy and Pharmacology Communications	0	0
174	1995	Antiplatelet Effect of Gingerol Isolated from Zingiber officinale	JIH-HWA GUH ; KO F.?N.; JONG T.?T.; TENG C.?M.	Journal of Pharmacy and Pharmacology	94	65
175	1995	Characterization of α1?adrenoceptor subtypes in tension response of human prostate to electrical field stimulation	JIH-HWA GUH ; SHIH-CHIEH CHUEH ; Ko F.?N.; Teng C.?M.	British Journal of Pharmacology	43	43
176	1995	Pharmacological evaluation of N-methyl-actinodaphnine, a new vascular α-adrenoceptor antagonist, isolated from Illigera luzonensis	JIH-HWA GUH ; Ko F.-N.; Yu S.-M.; Wu Y.-C.; Teng C.-M.	European Journal of Pharmacology	19	16
177	1995	Mechanism of anti-proliferation caused by YC-1, an indazole derivative, in cultured rat A10 vascular smooth-muscle cells	Yu S.M.; Cheng Z.J.; JIH-HWA GUH ; Lee F.Y.; Kuo S.C.	Biochemical Journal	24	24
178	1994	Functional identification of α1-adrenoceptor subtypes in human prostate: comparison with those in rat vas deferens and spleen	Teng C.-M.; JIH-HWA GUH ; Ko F.-N.	European Journal of Pharmacology	37	34
179	1994	(−)‐Discretamine, a selective α1D‐adrenoceptor antagonist, isolated from Fissistigma glaucescens	Ko F.-N.; JIH-HWA GUH ; Yu S.-M.; Hou Y.-S.; Wu Y.-C.; CHE-MING TENG	British Journal of Pharmacology	79	72

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